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Monday, 5 December 2016

RADIOTHERAPY

     


      Nowadays, the new technology does not strange to us anymore. Since we are already in 21 Century the new technology keeps on and on especially the technology that has been used in medical science to treat numerous of disease such as radiotherapy. Radiotherapy or radiation therapy is a new advanced technology that's been used in cancer and tumour disease treatment. Radiotherapy used high energy ray to destroy and treat the cancer tissue by exposing that tissue to the ray. This may be used with other treatment such as surgery and chemotherapy.

      Radiotherapy has been discovered by a Germany physician named Wilhem Rothgen which is the first person discovered the x-ray. It's been used by another physician to diagnose broken legs and allocated the foreign substance in the body on certain part. Following year in 1896, the other scientist Antoine-Henri Becquerel discovered a certain element called radioactivity that spontaneously emitted ray. After that, Becquerel has collaborated with Pierre and Marie Curie to find more about the element of radioactive.

      Finally, they have discovered the new radioactive which is radium and later on they found that radium can be used to kill the cancer cells. Emil Grubbe is a student doctor in Chicago became a first person that has been used x-rays radiation to cure the cancer.






Saturday, 3 December 2016

TRUEBEAM





      Today, this kind of radiotherapy that used to treat cancer has been upgraded with more high technology being used in that system. The new system (TrueBeam) that's being used nowadays brought a lot of special characteristics and been modified by using high energy ray to spot the cancer or tumour without destroying the healthy tissues.

      TrueBeam is more fast, accurate and efficient compared to the other system. Other than that, TrueBeam usually only took a few minutes to do the diagnoses and treatment to patients than older system or surgery which usually took almost an hour. This system is generated by a machine called Medical Linear Accelerator that integrates imaging and radiation delivery. The Truebeam can be targeted at a tumor from any angles in three-dimensional shape to know its size, shape, and location. It also rotated around the patients to deliver the amount of radiation needed in correct angles with submillimetre accuracy and varying intensity. There are two types technique that has been used in the TrueBeam such as Intensity Modulated Radiotherapy (IMRT) and Image Guided Radiotherapy (IGRT).





CHARACTERISTIC OF TRUEBEAM


Latest Treatment
  • IMRT
  • IGRT
  • Gated RapidArc
  • SBRT
  • SRS     

Enhanced Imaging System.
  • TrueBeam kV Paired Imaging.
  • TrueBeam Cone Beam CT – CBCT
  • TrueBeam MV Imaging.
  • TrueBeam Fluoroscopy.
  • Gated RapidAch Technology - produce a 3D image with 360 degrees of rotation 60% faster compared to the other technology with 25% lesser of usage dose.

Open Interface.
  • Calypso system, the positioning device.
  • Monitor the moving tumour at the real time.
  • ARIA® oncology information system.
  • Capable to transfer big files data such as the imaging picture files
  • The gated RapidArc system.
  • Enable third party clinicians monitoring the motion of tumour.

Fast and Precise.
  • Deliver treatment up to 50% faster compared to the previous version of Varian technology.
  • IGRT and CBCT can be done in 60% less time and 25% less dose compared to other technology.
  • Pinpoint accuracy.
  • Performs accuracy checks every ten milliseconds throughout the entire treatment.

FEATURE OF TRUEBEAM
      The TrueBeam system boasts multiple layer of safety for patient, the system component and the user. Among the system's safeguard area physical, software, audible and visual mechanism specifically designed to help ensure safe operation of the treatment. These features work together to help improve patient safely, while allowing clinicians to navigate the complexities of cancer care with coincidence.

  • Touch Ground
These components include the KV imaging panel, KV imaging source, the MC imaginKVpanel and if unskilled, the lower portion of the electron applicator.

  • Capacitive Collision Detection System
These components are a non-contact layer of safety that stops the motion of the KV imaging source if the active area is encroached upon.

  • Machine Motion Model
These components provide a 3D representation of the mechanical aspects of the entire system and prevent component-to-component collision.

  • Zone Rules
The component is motion restriction safeguards which prevent hardware collision. It is also restricting any remote and some targeted motions from being performed during patient setup and treatment delivery if the system detects that a collision is possible.

  • Live View Monitoring System
These systems act as a virtual presence, allowing the therapist to remain focused on the patient.

  • Visual and Audio Monitoring System
This visual mechanism affords the user ample coverage of the treatment room with pan, tilt and zoom capabilities for optimal viewing. The audio mechanism enables constant interaction between the patient and therapist.

  • Standardized User Interfaces
The pendants, couch side panel and treatment control console are all icon driven and use the same optical indicators for consistency and ease of recognition.

  • Pre-treatment Dry Run Capability
Dry run is used to verify motion clearance prior to executing a plan with beam delivery. The dry run functionality moves all Truebeam external motion axes through their planned movement for the entire treatment, but does not deliver any dose to the patient.

  • Laserguard II Infrared Laser Collision 
Laserguard II is an integrated patient and equipment collision detection system. The system uses an infrared laser scanning device that continuously monitors the contoured region between the collimator face and patient. If an object enters its protection zone, then Laserguard II stops motion prior to a potential collision





Input Process of TrueBeam
  1. The data captured after using the TrueBeam Varian treatment are transfer to the Treatment Planning System (TPS) to generate treatment plan
  2. A physicist check the plan quality and evaluate its deliverability then approve.
  3. The plan are sent to the Treatment Management System (TMS)
  4. The plan are then transferred to the linear accelerator(fastest straight pathway of data) for delivery.
  5. The treatment plan from TPS sent through DICOM to the database (network drive)
  6. For analysis, the TrueBeam trajectory log files of the treatment plan are recorded and transfer to the database (network drive).  

Processing Of Truebeam
  1. The TrueBeam Varian Medical Systems, a new log file called trajectory log file system.
  2. By using the new log trajectory log file system the data will provide a definite Quality assurance (QA)-Quality Control (QC) check which can increase the safety of Radiation Therapy (RT).
  3. The log file will find the patient ID then compare the delivered data against their original planned values of their jaw position, the beam energy, the gantry angle, the collimator angle, couch angle and the number of segments used for the next treatment.
  4. This TrueBeam log file analysis has an ability to catch any error related to data transfer quality without any additional effort.
  5. The comparison between The TrueBeam log files from the database with the DICOM treatment plan files exported from treatment planning system (TPS).



Output Process
    1. The MATLAB (MathWorks, Natick, MA) software use the beam on-off status and MultiLeaf Collimator (MLC) leaf positions from the TrueBeam log files to calculate and reconstruct the equivalent fluence map.
    2. The MLC positions recorded in the log files are then will be validated by a physicist.
    3. The QA are checked manually weekly to reduce any possible error.
    4. Automatic TrueBeam trajectory log file analysis ensure the data delivery quality,it is efficient, accurate, used less human involvement that might cause error during data input process.
    5. The data are printed into report for the physicist informan.
     
     
      Image result for truebeam structure
      Overall Process








      Monday, 28 November 2016

      MACHINE PERFORMANCE CHECK (MPC)







            MPC is an application to verify geometry and beam performances of Truebeam Linac, through automated checks based on their kV-MV imaging systems. Data acquisition in MPC comprises a series of 39 images (12 with kV and 27 with MV detector) acquired at predefined positions without and with the IsoCal phantom in the beam and with particular MPC pattern settings.

            MPC performs geometric and dosimetric checks. The geometric checks intend to test the treatment isocenter size and its coincidence with imaging devices, the positioning accuracy of the imaging systems, the collimator, the gantry, the jaws, the MPC leaves and the couch position. The dosimetric checks refer to a reference MV image and give the beam output, uniformity and center change relative to the reference.





      FEATURE OF MPC


            The Machine Performance Check (MPC) is a new Truebeam major mode, designed to evaluate the machines geometric performance in five minutes. It employs a fully automated measurement sequence that uses the kV and MV imaging systems and the proven IsoCal phantom. The IsoCal phantom is a hollow cylinder 23 cm in diameter and length with 16 tungsten-carbide bearing balls (each 4 mm in diameter). For imager system calibration it uses a collimator plate attached to an accessory slot, having a steel pin in its center. For MPC implementation, the IsoCal phantom does not use such as a collimator plate and it is mounted to the couch top using a dedicated holder (figure a).

            The operator enters into the MPC mode at the Truebeam console (figure b) and just initiates the procedures that takes place automatically. MPC automatically acquires a series of MV and KV images, moving the machine and imaging systems in the pre-defined position. The two detector panels are positioned at a distance of 150 cm from the source. The images are immediately processed and the result displayed for a quick evaluation, indicating whether the values are within system specifications (figure c), exported and reported.

             The predefined acquisitions consist of a set of 39 images, 12 acquired by kV (XI system) with the IsoCal phantom in the field, 27 with MV (detected on the portal vision system) of which 20 are with and 7 without the IsoCal phantom in the field. The 39 images are the input for the machine performance parameter evaluation.

            MPC has been here evaluated for the five photon energies available on our Truebeam machine: 6, 10 and 15 MV and 6,10 MV FFF.

            For most of the MPC checks, an independent control has been performed at the same time of the acquisition of the MPC to evaluate the agreement of the two methods. For the independent checks, the here used procedures, phantoms and detectors were those available in the department and routinely used for quality assurance.




      DISADVANTAGE OF MPC

            Clearly MPC has contribute a major role in verifying geometry and beam performance of TrueBeam Linacs,by showcasing its reliableness,fast and easy to use method.But somehow, the MPC contains drawbacks of its own. These disadvantages includes the absence of linearity check in MPC and the fact that MPC is not a true QA tool.


      • Absence of Linearity Check in MPC


            Linearity check in MPC is a must have as it contributes to determine the linear reportable range for the TrueBeam. The MPC evaluates the machines geometric performance. It employs a fully automated measurement sequence that uses the KV and MV imaging systems and the proven IsoCal phantom. This process gives out a list of data. Everything that affects the data, for good or bad, is reflected one way or another on the table and the graph to be plotted.
            The Linearity of the graph indicates higher accuracy and precision. Once the linearity check has been performed, then only the calibration verification can be executed in accordance with the Clinical Laboratory Improvement Amendments (CLIA) to verify the continued acceptable performance.



      • MPC is not a true QA tool

            Quality assurance (QA) tool is a tool used to measure and assure the quality of a product and quality control, the process of ensuring products and services meet consumer expectations. MPC is not considered as a true QA tool as it does not replace the need to perform a QA routine. MPC just acts as an application to verify geometry and beam performances of TrueBeam Linacs, through automated checks based on their KV-MV imaging systems but never influence the quality of the product produced.






      IMPACT OF NOT USING MPC


      Other Application Similar with (MPC)


      • Artemis RapidArc
      • Flattening Filter Free (FFF)
      • Catalyst HD 
       

            However, there are some differences of Machine Performance Check (MPC) with other application stated above.

      • Different Parameters


            MPC evaluated five different photon energies for different parameters which is 6MV, 10MV, 15MV, 6MV FFF and 10MV FFF. Compared to other application of Truebeam, they evaluated different ranges of photon energies of different parameters.

      • Accuracy of Results


            Treatment of IsoCentre of MPC determined by the IsoCal phantom gives the accuracy and detail result in the review workspace where the result of each test is possible to be analysed and trended. While the other application such as Catalyst HD may display IsoCentre error because of the IsoCentre is sometimes established by moving planned coordinates alone while Catalyts is running.



      Results are shown in the review workspace in very detail. Detailed test results on the left side and acquired images and analysis on the right.
      • Position Accuracy


            MPC measure the position accuracy of different couch axes using a reference position that was established as fixed room coordinate system using KV and MV images with IsoCal phantom. Whereas, other application such as Catalyst HD on Truebeam uses different mode setting which is cPosition and cMotion in order to positioning the patient correctly on the couch using the only one-beam-before-MV images.


      The IsoCal phantom mounted on the couch top